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Genetics of emotional regulation

 

 
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The second most read article in TICS (see previous headline) is a review (PDF) of studies from imaging genetics, the study of how genes make up our minds, as we have described here at SCR. Ahmad Hariri and Andrew Holmes reviews the evidence and discusses the implications of the genetic regulation of serotonin function on […]

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Posted October 4, 2006 by thomasr

 
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amygdala1.jpg The second most read article in TICS (see previous headline) is a review (PDF) of studies from imaging genetics, the study of how genes make up our minds, as we have described here at SCR. Ahmad Hariri and Andrew Holmes reviews the evidence and discusses the implications of the genetic regulation of serotonin function on both brain function and behaviour in emotions. Abstract:

Hariri AR, Holmes A
Trends Cogn Sci. 2006 Apr ; 10(4): 182-91

Identifying biological mechanisms through which genes lead to individual differences in emotional behavior is paramount to our understanding of how such differences confer risk for neuropsychiatric illness. The emergence of techniques such as in vivo imaging of brain function in humans and genetic engineering in rodents has provided important new insights into the impact of serotonin (5-HT), a key modulator of emotional behavior, on neural systems subserving anxiety and depression. A major finding has been the discovery of genetic variation in a crucial regulatory molecule within the 5-HT system, the 5HT transporter (5-HTT), and its influence on emotional traits. The study of the 5-HTT provides a new foundation for understanding the neurobiological and genetic basis of emotional regulation and affective illness.

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thomasr

 


One Comment


  1.  
    nate

    does genetic traist & emotion behavior have a connection





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